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Favism, the commonest form of severe hemolytic anemia in Palestinian children, varies in severity with three different variants of G6PD deficiency within the same community
(Academic Press, 2016)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common genetic abnormality known to predispose to acute hemolytic anemia (AHA), which can be triggered by certain drugs or infection. However, the commonest trigger ...
Clinical Significance of G6PD Variants among Palestinians
(ELSEVIER SCIENCE INC, 2016)
Conclusion: We conclude that children with G6PD A-deficiency are also susceptible to AHA, but demonstrate in direct comparison within this same population that G6PD Mediterranean and G6PD Cairo are more severe forms of ...
Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Gaza Strip Palestinians
(Academic Press, 2012)
Background
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting more than 500 million people worldwide, is one of the most common of inherited disorders. There are 186 G6PD mutations published, with mutational ...
G6PD Deficient Variants Differ in Risk of Hospitalization Among Gaza Strip Palestinian Children
(American Society of Hematology, 2012)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting more than 500 million people worldwide, is one of the most common inherited disorders. There are 186 G6PD mutations published, with some that cluster within ...
Hemolysis and Mediterranean G6PD mutation (c. 563 C> T) and c. 1311 C> T polymorphism among Palestinians at Gaza Strip
(Academic Press, 2012)
Background
The G6PD c.563 C > T deficient mutation is endemic among Mediterranean populations but its clinical significance is not well delineated. We set up to estimate the proportion of G6PD deficient children presenting ...
G6PD Deficiency in Palestinian children increases risk of hospitalization which differs according to G6PD variant
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, affecting more than 500 million people worldwide, is one of the most common inherited red blood cell disorders. There are 186 G6PD mutations published, with some that ...