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Taxifolin synergizes Andrographolide-induced cell death by attenuation of autophagy and augmentation of caspase dependent and independent cell death in HeLa cells

AL Zaharna, Mazen Medhat; EL Qouqa, Iyad A; Cheung, Hon-Yeung (2017)

Andrographolide (Andro) has emerged recently as a potential and effective anticancer agent with induction of apoptosis in some cancer cell lines while induction of G2/M arrest with weak apoptosis in others. Few studies ...

In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine

Yang, Mei; AL Zaharna, Mazen Medhat; Chen, Yu-Shan; Li, LI; Cheung, Hon-Yeung (Royal Society of Chemistry, 2014)

Abrus cantoniensis is a common and popular vegetative food consumed as beverage, soup and folk medicine in the tropical and subtropical areas of Asia. It has been claimed valuable for cleansing toxicants in the liver. ...

Achieving Synergistic Effects by Combining Different Phytochemicals for the Prevention and Treatment of Cancer

AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (Hong Kong Pharmaceutical Journal, 2014)

AL ZAHARNA, M & CHEUNG, HY 2014, 'Achieving Synergistic Effects by Combining Different Phytochemicals for the Prevention and Treatment of Cancer' Hong Kong Pharmaceutical Journal, vol 21, no. 1, pp. 20 - 24 … AL ZAHARNA, ...

Anticancer effect of andrographolide on cell cycle, apoptosis and autophagy of human breast carcinoma cells

EL Qouqa, Iyad A; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2014)

ALQOUQA, IAS, AL ZAHARNA, MMM & CHEUNG, HY 2014, 'Anticancer effect of andrographolide on cell cycle, apoptosis and autophagy of human breast carcinoma cells' 10th International Postgraduate Symposium on Chinese medicine ...

The combination effect of andrographolide and taxifolin on cell proliferation, cell cycle, apoptosis and autophagy of HeLa cells

AL Zaharna, Mazen Medhat (2014)

Andrographolide (Andro), the major bioactive constituent of the Andrographis paniculata herba, has been recently shown to have potent cytotoxic effects in a dose dependent manner against different kinds of cancer cells. ...

Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation

Zhang, Zhong Rong; AL Zaharna, Mazen Medhat; Wong, Matthew Man-Kin; Chiu, Sung-Kay; Cheung, Hon-Yeung (Public Library of Science, 2013)

Andrographolide (Andro) suppresses proliferation and triggers apoptosis in many types of cancer cells. Taxifolin (Taxi) has been proposed to prevent cancer development similar to other dietary flavonoids. In the present ...

Comparison Study of HPLC Profiles and Antioxidant Activities of Traditional Chinese Herb Abri Cantoniensis and Abri Mollis

Yang, Mei; AL Zaharna, Mazen Medhat; Zhang, Zhifeng; Huang, Yeqing; Cheung, Hon-Yeung (2013)

Abri cantoniensis (AC) is regarded as a potent folk medicine for jaundice, hepatitis for long history worldwide. Abri Mollis (AM) is an alternative species of AC. In the present study, the high performance liquid chromatography ...

AFM and Proteomic Analysis of Spore Coat Related to Spore Germination of Geobacillus stearothermophilus

Dong, W; Shen, Q; AL Zaharna, Mazen Medhat; Zhang, Zhong Rong; Cheung, Hon-Yeung (2013)

DONG, W, SHEN, Q, AL ZAHARNA, M, ZHANG, Z & CHEUNG, HY 2013, 'AFM and Proteomic Analysis of Spore Coat Related to Spore Germination of Geobacillus stearothermophilus' Paper presented at 2nd International Conference on ...

PROTEOMIC ANALYSIS OF GERMINATION-ASSOCIATED PROTEINS OF GEOBACILLUS STEAROTHERMOPHILUS

Wei, Dong; Qing, Shen; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2013)

DONG, W, SHEN, Q, AL ZAHARNA, M & CHEUNG, HY 2013, 'PROTEOMIC ANALYSIS OF GERMINATION-ASSOCIATED PROTEINS OF GEOBACILLUS STEAROTHERMOPHILUS' Paper presented at International Symposium on Translating Omics Science to Clinical ...

ETHYL ACETATE FRACTION OF ABRI CANTONISIS HERBA INDUCES CELL CYCLE ARREST AT G2/M PHASE IN HUMAN CERVICAL CANCER CELL LINE HELA

Mei, Yang; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2013)

YANG, M, AL ZAHARNA, M & CHEUNG, HY 2013, 'ETHYL ACETATE FRACTION OF ABRI CANTONISIS HERBA INDUCES CELL CYCLE ARREST AT G2/M PHASE IN HUMAN CERVICAL CANCER CELL LINE HELA' Paper presented at International Symposium on ...