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Association between functional polymorphisms of Foxp3 and Interleukin-21 genes with the occurrence of recurrent pregnancy loss in Gaza strip-Palestine

Jaber, Mohammed O; Sharif, Fadel A. (2017)

Background: This study was conducted in order to investigate the association between IL-21 (rs2055979 G/T and rs13143866 A/G) and Foxp3 (rs2232365 A/G and rs3761548 A/C) gene polymorphisms and recurrent pregnancy loss (RPL) ...

Endothelial nitric oxide synthase (eNOS) gene polymorphism, nitric oxide and progesterone levels in unexplained recurrent pregnancy loss

El-Gharably, Emad M; Sharif, Fadel A. (2017)

This study was conducted in order to determine the relationships between promoter-786 T> C, exon 7 Glu298Asp (894 G> T) and intron 4 (4a4b) VNTR polymorphisms of eNOS gene, serum nitric oxide (NO) and progesterone (P4) ...

Nphs2 Mutations in Familial Steroid Resistant Nephrotic Syndrome in Gaza

Sharif, Fadel A. (2017)

Background: Nephrotic syndrome (NS) is characterized by edema, massive proteinuria, hypoalbuminemia, hyperlipidemia, and may progress to end stage renal disease. Based on the response to steroid therapy, NS is categorized ...

The single nucleotide polymorphism rs2305957 G/A is not associated with recurrent pregnancy loss

Sharif, Fadel A.; Ashour, Mohammed J. (2017)

Background: This study was conducted in order to investigate the association between the single nucleotide polymorphism (SNP) rs2305957 G/A and recurrent pregnancy loss (RPL) in a group of Palestinian women residing in ...

HLA-G and HLA-E Gene polymorphisms in idiopathic recurrent spontaneous abortion women in Gaza strip-Palestine

Matter, Tamam F; Sharif, Fadel A. (2016)

Human leukocyte antigens (HLA)-G and HLA-E are non-classical HLA class I antigens expressed on extravillous cytotrophoblast that invades decidua in the uterus during pregnancy and are postulated to help in maternal ...

Dysregulation of micro-RNA contributes to the risk of unexplained recurrent pregnancy loss

El-Shorafa, Heba M; Sharif, Fadel A. (2016)

Although there are plenty of evidence that dysregulation of microRNA (miRNA) level is involved in many human diseases, it is still unknown whether abnormal levels of specific miRNAs are associated with recurrent pregnancy ...

Polymorphism in Regulatory T-cell (Treg)-Related Genes Is Associated with Unexplained Recurrent Pregnancy Loss

Al-Ashi, Shadi F; Sharif, Fadel A.; Ashour, Mohammed J.; Badawi, Naim T. (Science Publishing Group, 2016)

In the absence of confirmed causes for around 50% of recurrent pregnancy loss (RPL) cases this study was conducted in order to investigate the association between single nucleotide polymorphism (SNP) in regulatory T-cell ...

Beta-fibrinogen (-455 G/A) and Integrin beta-3 (PLA1/A2) polymorphisms and recurrent pregnancy loss in Gaza strip-Palestine

Al-Astal, Manal G; Sharif, Fadel A. (2016)

Background: This study was conducted in order to determine the relationship between the common polymorphisms in β-fibrinogen-455 G/A (rs1800790) and Integrin beta-3 T196C (PLA1/A2, rs5918) and recurrent pregnancy loss (RPL) ...

Familial reciprocal translocation t (8; 17)(p23; q21) in a woman with recurrent spontaneous abortion

Al-Ashi, Shadi F; Sharif, Fadel A. (2016)

This work presents the results of cytogenetic analysis of a couple referred to our genetics laboratory with ten first trimester abortions and one IVF failure. The male showed a normal (46, XY) karyotype whereas the female ...

Glycodelin (PAEP) gene promoter polymorphism rs760140467 C>T is associated with recurrent pregnancy loss

Sharif, Fadel A. (www.ijmrhs.com, 2016)

In the absence of confirmed causes for around 50% of recurrent pregnancy loss (RPL) cases this study was conducted in order to evaluate the relationship between PAEP gene single nucleotide polymorphism (SNP) rs760140467 ...

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