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|Title||IN VITRO, INTERACTION OF SOME ANTIBIOTICS WITH DIFFERENT FRUIT EXTRACTS ON SOME PATHOGENIC BACTERIAL STRAINS|
|Title in Arabic||فعالية بعض المضادات الحيوية مع بعض مستخلصات الفاكهة ضد بعض الكائنات الممرضة في المعمل|
Objective:To evaluateinvitro, the synergistic effects of bioactive extracts ofPunica granatum(Pomegranate) "pulp", Actinidia deliciosa(Kiwifruit) "peel" and Citrus maxima(Pomelo) "pulp" with different antibiotics against Staphylococcus aureus, Escherichia coliandPseudomonas aeruginosa.Methods:The extraction was carried out using the soxhlet in presence of ethanol, methanol or water. Evaluation of synergistic activity was carried out using disc diffusion method.Results:Theresultspointed that some of crude extracts showed a synergistic activity against the tested bacteria, and some extract showed no synergistic effect. The highest synergistic effect was observed with streptomycin and ciprofloxancin. Conclusion: Obviously the wide use of antibiotics in the treatment of bacterial infections has led to spread of resistant strains so we need to find a source of bioactive substances that could possess broad spectrum of activity when it is combined with antibiotic to be able resist the pathogenic microorganism.
|Published in||International Journal of Development Research|
|Series||Vol. 6, Issue 4|
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