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http://hdl.handle.net/20.500.12358/26334
TitleReaction of Nitrilimines with 2-Substituted Aza-heterocycles. Synthesis of Pyrrolo [1, 2-a] pyridine and Pyrimido [2, 1-d] 1, 2, 3, 5-tetrazine
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Abstract

The reaction of nitrilimine 6a with ethyl pyridine-2-acetate (7) gave thecorresponding pyrrolo&91;1,2-a&93;pyridine 8, while the reaction of 6b containing an estermoiety afforded the acyclic adduct 9. The reaction of 6a with 2-aminopyrimidine (10)gave the novel unexpected pyrimido&91;2,1-d&93;1,2,3,5-tetrazine 11. Acyclic adducts 16 and17 were obtained from the reaction of 6b with 2-cyanomethylbenzimidazole (14) and 2-aminobenzimidazole (15), respectively.

Authors
Awadallah, Adel M.
Zahra, Jalal A
TypeJournal Article
Date2008
Subjects
Nitrilimines
ethyl pyridine-2-acetate
pyrrolo[1,2-a]pyridine
2-amino- pyrimidine
pyrimido[2,1-d]1,2,3,5-tetrazine
2-cyanomethylbenzimidazole
2-amino- benzimidazole
Published inMolecules
SeriesVolume: 13, Number: 1
PublisherDirectory of Open Access Journals
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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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