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http://hdl.handle.net/20.500.12358/26225
Title | 3-Mercaptopropionic acid–nitrile imine adducts. An unprecedented cyclization into 1, 3, 4-thiadiazol-2 (3 H)-ones and-2 (3 H)-thiones |
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Untitled | |
Abstract |
3-Mercaptopropionic acid–nitrile imine acyclic adducts (6a–c) undergo cyclocondensation with 1,1′-carbonyldiimidazole to afford the respective 1,3,4-thiadiazol-2-(3H)-ones (7a–c). Corresponding 1,3,4-thiadiazol-2(3H)-thiones (8a–c) were likwise produced from 6a–c and 1,1′-thiocarbonyldiimidazole, with consequent elimination of the propionate moiety. The constitution of these heterocyclic products follows from analytical and spectral data and is confirmed by single crystal X-ray structure determination for 7b. |
Type | Journal Article |
Date | 2005 |
Published in | Organic & biomolecular chemistry |
Series | Volume: 3, Number: 14 |
Publisher | Royal Society of Chemistry |
Citation | |
Item link | Item Link |
License | ![]() |
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