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http://hdl.handle.net/20.500.12358/26196
Title | Ring Size Influence on the Cyclocondensation Mode of GABA–Nitrile Imine Adducts |
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Untitled | |
Abstract |
γ-Aminobutyric acid (GABA) adds onto nitrile imine 1, 3-dipolar species (generated in situ from their N-arylhydrazonoyl chloride precursors 1a-c) to deliver the corresponding acyclic amidrazone adducts 10a-c. In the presence of 1, 1’-carbonyldiimidazole, the latter adducts undergo cyclocondensation involving the activated carboxyl and the amidrazone-CH 2 NH groups to afford the respective N-[1-(arylhydrazono)-2-oxopropan-1-yl] pyrrolidin-2-ones (11a-c). The constitution of 10 and 11 is evidenced from analytical and spectral (IR, MS and NMR) data. |
Type | Journal Article |
Date | 2004 |
Published in | Zeitschrift für Naturforschung B |
Series | Volume: 59, Number: 8 |
Publisher | Verlag der Zeitschrift für Naturforschung |
Citation | |
Item link | Item Link |
License | ![]() |
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