On the synthesis of 3-acetyl-1-aryl-1, 4, 5, 6-tetrahydro-1H-1, 2, 4-triazepin-7-ones by reaction of nitrilimines with 3-aminopropanoic acid

Abstract

Nitrilimines were prepared from N-arylhydrazono chlorides and reacted with β-alanine yielding the corresponding amidrazones, which were treated with 1,1′-carbonyldiimidazole in THF affording the hitherto unknown 3-acetyl-1-aryl-1,4,5,6-tetrahydro-1,2,4-triazepin-7-ones.