Synthesis and properties of some new 5-fluoro-6-(heterocyclyl) benzofuroxans

Abstract

A series of 5-fluoro-6-(heterocyclyl) benzofuroxans (3b-e) have been prepared by hypochlorite oxidative cyclization of the respective 4-fluoro 5-(N-heterocyclyl)-2-nitroanilines (2b-e). The heterocyclyls include piprazine, N-(2-hydroxyethyl) piprazine, morpholine and thiomorpholine. Some bio-properties and spectral data these new derivatives are presented.