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http://hdl.handle.net/20.500.12358/25379
TitleScreening for Y-chromosome microdeletions in a population of infertile males in the Gaza Strip
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Abstract

Infertility is an extraordinary public health problem in the Arab world, as it affects about 15% of couples seeking children. The male partner is responsible for infertility in approximately half of these cases. Classic microdeletions of the Y-chromosome involving the azoospermia factor (AZF) regions are known to be associated with spermatogenic impairment, and non-obstructive azoospermia must be differentiated on the basis of endocrine evaluation and testicular biopsy. Partial AZFc deletions remain controversial because there is no clear agreement regarding their role in spermatogenic failure. In the current study, 50 fertile males (controls) and 125 patients with primary idiopathic male infertility were studied in order to describe the frequency of Y-chromosome mirodeletions among male infertility patients in the Gaza Strip-Palestine area. No Y chromosome classical microdeletions could be detected in any of the 125 …

Authors
Shaqalaih, Ashraf J
Abu Halima, Masood SH
Ashour, Mohammed J.
Sharif, Fadel A.
TypeJournal Article
Date2009
Subjects
a/oligozoospermia
azfc partial deletion
idiopathic male infertility
y-chromosome microdeletions
Published inJournal of experimental & clinical assisted reproduction
SeriesVolume: 6
PublisherSims Institute Press Ltd.
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  • Staff Publications- Faculty of Health Sciences [192]
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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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