• العربية
    • English
  • English 
    • العربية
    • English
  • Login
Home
Publisher PoliciesTerms of InterestHelp Videos
Submit Thesis
IntroductionIUGSpace Policies
JavaScript is disabled for your browser. Some features of this site may not work without it.
View Item 
  •   Home
  • Faculty of Medicine
  • Staff Publications- Faculty of Medicine
  • View Item
  •   Home
  • Faculty of Medicine
  • Staff Publications- Faculty of Medicine
  • View Item

Please use this identifier to cite or link to this item:

http://hdl.handle.net/20.500.12358/24406
Titleη4-Pyrone iron(0)carbonyl complexes as effective CO-releasing molecules (CO-RMs)
Untitled
Abstract

The CO-releasing properties of iron(0)tricarbonyl complexes bearing a 2-pyrone ligand have been evaluated. In this report, we demonstrate that the intrinsic stability of the (η4-2-pyrone)Fe(CO)3 complex influences the extent and rate of CO release, which is affected by the presence of a halogen substituent on the 2-pyrone ring. The cell viability index has been highlighted for the active carbon monoxide-releasing molecules (CO-RMs), demonstrating that these complexes and related derivatives are a promising new class of compounds with potential therapeutic applications.

Authors
Fairlamb, Ian JS
Duhme-Klair, Anne-kathrin
Lynam, Jason M
Moulton, Benjamin
O'brien, Ciara T
Sawle, Philip
Hammad, Jehad
Motterlini, Roberto
TypeJournal Article
Date2006
Published inBioorganic & medicinal chemistry letters
SeriesVolume: 16, Number: 4
PublisherPergamon
Citation
Item linkItem Link
License
Collections
  • Staff Publications- Faculty of Medicine [149]
Files in this item
There are no files associated with this item.

The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

Contact Us | Send Feedback
 

 

Browse

All of IUGSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsSupervisorsThis CollectionBy Issue DateAuthorsTitlesSubjectsSupervisors

My Account

LoginRegister

Statistics

View Usage Statistics

The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

Contact Us | Send Feedback