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http://hdl.handle.net/20.500.12358/24131
Titleمقارنة مستوي الاجسام المضادة ضد بروتين السيترولين 2 مع عامل الروماتزم في تشخيص التهاب المفاصل الروماتزمي في قطاع غزة
Title in Arabicمقارنة مستوي الاجسام المضادة ضد بروتين السيترولين 2 مع عامل الروماتزم في تشخيص التهاب المفاصل الروماتزمي في قطاع غزة
Abstract

Objectives: To compare the diagnostic value and clinical utility of Anti cyclic citrullinated protein 2 antibody (ACCP2A) with IgM rheumatoid factor (IgM RF) in patients with rheumatoid arthritis (RA). Methods: In a cross sectional study, we determined titers of these markers in 67 arthritis patients and 75 healthy controls by enzyme linked immuno-sorbent assay (ELISA). C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were also assayed as inflammatory parameters for all subjects. All clinical features were investigated by a rheumatologist and questionnaire interviews. And all results were analyzed by SPSS version "15". Results: sensitivity was higher for IgM RF (85%) than ACCP2A (56%) but specificity was higher for ACCP2A (99%) than IgM RF (69%). When the two antibodies were used together, sensitivity and specificity reached 88% and 100%. A correlation with extra articular manifestations, severity of erosions and CRP was observed for both tests.

Authors
Skaik, Bushra M
Shubair, Mohammad E.
El Hindi, Marwan
TypeJournal Article
Date2010
Languageالعربية
Published inIUG Journal for Natural and Engineering Studies
SeriesVolume: 18, Number: 1
Publisherالجامعة الإسلامية - غزة
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  • Staff Publications- Faculty of Health Sciences [253]
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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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