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http://hdl.handle.net/20.500.12358/24061
Title | Incorporating Thiobarbituric Acid with 1,2,4-Triazin-6-one Containing Nitroarginine Moiety |
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Abstract |
Abstract : Nitrilimines (2a,b), react with nitroarginine methyl ester (3) at room temperature, through cyclocondensation reaction, to give 1-aryl-3-substituted-1,2,4-triazin-6-ones (4a,b). Condensation of these compounds with thiosemicarbazide give the thiosemicarbazone derivatives (5a,b ) which upon heterocyclization with malonic acid give the thiobarbituric acid derivatives (6a,b). The structures of these compounds were deduced from: IR, mass, 1H and 13C NMR spectra. Keywords Nitrilimine , nitroarginine methyl ester, 1,2,4-triazin-6-ones, thiosemicarbazone, thiobarbituric acid derivatives. |
Type | Journal Article |
Date | 2014 |
Language | English |
Published in | IUG Journal for Natural and Engineering Studies |
Series | Volume: 22, Number: 2 |
Publisher | الجامعة الإسلامية - غزة |
Citation | |
License | ![]() |
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