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http://hdl.handle.net/20.500.12358/24061
TitleIncorporating Thiobarbituric Acid with 1,2,4-Triazin-6-one Containing Nitroarginine Moiety
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Abstract

Abstract : Nitrilimines (2a,b), react with nitroarginine methyl ester (3) at room temperature, through cyclocondensation reaction, to give 1-aryl-3-substituted-1,2,4-triazin-6-ones (4a,b). Condensation of these compounds with thiosemicarbazide give the thiosemicarbazone derivatives (5a,b ) which upon heterocyclization with malonic acid give the thiobarbituric acid derivatives (6a,b). The structures of these compounds were deduced from: IR, mass, 1H and 13C NMR spectra. Keywords Nitrilimine , nitroarginine methyl ester, 1,2,4-triazin-6-ones, thiosemicarbazone, thiobarbituric acid derivatives.

Authors
Abu Thaher, Bassam A.
El-Abadla, Naser S.
Abdel-Rahman, Reda M.
EL- Nwairy, Khaled A.
TypeJournal Article
Date2014
LanguageEnglish
Published inIUG Journal for Natural and Engineering Studies
SeriesVolume: 22, Number: 2
Publisherالجامعة الإسلامية - غزة
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  • Staff Publications- Faculty of Science [1030]
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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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