SYNTHESIS OF SOME NEW SUBSTITUTED IMIDAZO(1,2-a)PYRIDINES AND THEIR 2-ONE DERIVATIVES

Abstract

2,3-diaminopyridine (11) (a tri-nitrogen nucleophile) undergoes regioselective cyclocondensation reaction with nitrilimines (2,10) affording 8-aminoimidazo[1,2-a]pyridines (12) and 8-aminoimidazo[1,2- a]pyridine-2- ones (13), respectively. The structures of the new compounds (12,13) were deduced from their IR, MS and NMR spectral data.