• العربية
    • English
  • English 
    • العربية
    • English
  • Login
Home
Publisher PoliciesTerms of InterestHelp Videos
Submit Thesis
IntroductionIUGSpace Policies
JavaScript is disabled for your browser. Some features of this site may not work without it.
View Item 
  •   Home
  • Faculty of Science
  • PhD and MSc Theses- Faculty of Science
  • View Item
  •   Home
  • Faculty of Science
  • PhD and MSc Theses- Faculty of Science
  • View Item

Please use this identifier to cite or link to this item:

http://hdl.handle.net/20.500.12358/21751
TitleGenetic Variation of 15 Autosomal Short Tandem Repeat (STR) Loci in the Palestinian Population of Gaza Strip
Untitled
Abstract

Allele frequencies for 15 autosomal Short Tandem Repeat (STR) loci namely Penta E, D18S51, D21S11, TH01, D3S1358, FGA, TPOX, D8S1179, vWA, Penta D, CSF1PO, D16S539, D7S820, D13S317, D5S818 and Amelogenin, were studied in a sample of 125 unrelated individuals from the Palestinian population of Gaza Strip. PCR amplification was performed with the PowerPlex® 16 PCR amplification system and the amplified products were separated and detected using the ABI 3130 DNA genetic analyzer using reference-sequenced ladder. No significant departure from Hardy Weinberg Equilibrium (HWE) expectations were observed for 11 of the 15 STR loci analyzed (P-value >0.05). The exceptions were the Penta E, D5S818, D13S317 and vWA loci but when the Bonferroni procedure was used as a correction for the multiple tests performed on a population sample, none of the previous P-values could be considered significant. No linkage disequilibrium was found between the loci located on the same chromosome, and thus they are statistically independent. The FIS value for Gazan population has been calculated as – 0.024. This low FIS value indicates that the population is in random mating with high level of heterozygosity. The combined probability of exclusion, power of discrimination, probability of matching value for all the 15 STR loci were 0.999998595; 0.999999986 and 2.73 x 10-18 , respectively. In the light of the obtained results, we can confidently conclude that these 15 markers are suitable for forensic analyses and paternity testing in the Palestinian population of the Gaza Strip.

Authors
Abu Halimah, Masoud Said Hasan
Supervisors
El-sharif, Fadel A.
Typeرسالة ماجستير
Date2008
LanguageEnglish
Publisherthe islamic university
Citation
License
Collections
  • PhD and MSc Theses- Faculty of Science [445]
Files in this item
file_1.pdf811.3Kb
Thumbnail

The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

Contact Us | Send Feedback
 

 

Browse

All of IUGSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsSupervisorsThis CollectionBy Issue DateAuthorsTitlesSubjectsSupervisors

My Account

LoginRegister

Statistics

View Usage Statistics

The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

Contact Us | Send Feedback