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Achieving Synergistic Effects by Combining Different Phytochemicals for the Prevention and Treatment of Cancer
AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (Hong Kong Pharmaceutical Journal, 2014)AL ZAHARNA, M & CHEUNG, HY 2014, 'Achieving Synergistic Effects by Combining Different Phytochemicals for the Prevention and Treatment of Cancer' Hong Kong Pharmaceutical Journal, vol 21, no. 1, pp. 20 - 24 … AL ZAHARNA, ... -
AFM and Proteomic Analysis of Spore Coat Related to Spore Germination of Geobacillus stearothermophilus
Dong, W; Shen, Q; AL Zaharna, Mazen Medhat; Zhang, Zhong Rong; Cheung, Hon-Yeung (2013)DONG, W, SHEN, Q, AL ZAHARNA, M, ZHANG, Z & CHEUNG, HY 2013, 'AFM and Proteomic Analysis of Spore Coat Related to Spore Germination of Geobacillus stearothermophilus' Paper presented at 2nd International Conference on ... -
AFM evidence of inhibitory effects of alkaline glutaraldehyde on spore germination of Bacillus stearothermophilus
Cheung, Hon-Yeung; Wei, Dong; AL Zaharna, Mazen Medhat (2012)CHEUNG, HY, DONG, W & AL ZAHARNA, M 2012, 'AFM evidence of inhibitory effects of alkaline glutaraldehyde on spore germination of Bacillus stearothermophilus' 5th European Spore Conference, United Kingdom, 16/04/12 - 19/04/12 ... -
Anticancer activity of Rosemary (Rosmarinus officinalis L.) and Oats (Avena sativa L.) Extracts, and their antitumor enhancement of 5-Fluorouracil on Colon Cancer Caco-2 Cell Line
El-burai, Hadil; Alzaharna, Mazen; Isleem, Rajy; El-Hindi, Mahmoud; Sharif, Fadel (AKINI PUBLISHERS, 2020-04)Colorectal cancer is one of the commonest tumors worldwide, and the third cause of death among all cancers. Over the years, several herbal plants have proved efficacy in modulating this disease. In this study, plant parts ... -
Anticancer effect of andrographolide on cell cycle, apoptosis and autophagy of human breast carcinoma cells
EL Qouqa, Iyad A; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2014)ALQOUQA, IAS, AL ZAHARNA, MMM & CHEUNG, HY 2014, 'Anticancer effect of andrographolide on cell cycle, apoptosis and autophagy of human breast carcinoma cells' 10th International Postgraduate Symposium on Chinese medicine ... -
Calpain 10 Gene Polymorphism in Type 2 Diabetes Mellitus Patients in Gaza Strip
El Zaharna, Mazen . M (the islamic university, 2007)Calpain-10 (CAPN10) is a member of a large family of intracellular proteases. The polymorphisms at CAPN10 gene have recently been associated with complex forms of type 2 diabetes mellitus (T2DM). It was shown in Mexican-Americans ... -
Comparison Study of HPLC Profiles and Antioxidant Activities of Traditional Chinese Herb Abri Cantoniensis and Abri Mollis
Yang, Mei; AL Zaharna, Mazen Medhat; Zhang, Zhifeng; Huang, Yeqing; Cheung, Hon-Yeung (2013)Abri cantoniensis (AC) is regarded as a potent folk medicine for jaundice, hepatitis for long history worldwide. Abri Mollis (AM) is an alternative species of AC. In the present study, the high performance liquid chromatography ... -
ETHYL ACETATE FRACTION OF ABRI CANTONISIS HERBA INDUCES CELL CYCLE ARREST AT G2/M PHASE IN HUMAN CERVICAL CANCER CELL LINE HELA
Mei, Yang; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2013)YANG, M, AL ZAHARNA, M & CHEUNG, HY 2013, 'ETHYL ACETATE FRACTION OF ABRI CANTONISIS HERBA INDUCES CELL CYCLE ARREST AT G2/M PHASE IN HUMAN CERVICAL CANCER CELL LINE HELA' Paper presented at International Symposium on ... -
Extraction Methods of Cyanotoxins Aqueous Media and Sediments
El-Nahhal, Hala; Yassin, Maged; Alzaharna, Mazan; El-Nahhal, Ibrahim; El-Nahhal, Yasser (Scientific Research Publishing, Inc., 2021-09)Cyanotoxins are chemical compounds produced by cyanobacterial mats grown in aquatic ecosystems. These may threaten human health and aquatic organisms. Extraction of these toxins is usually associated with many difficulties due ... -
Genetic polymorphism and risk of having type 2 diabetes in a Palestinian population: a study of 16 gene polymorphism
Sharif, Fadel; Shubair, Mohammad; AL Zaharna, Mazen; Ashour, Mohammed (Avens Publishing Group, 2018)Background: Type 2 Diabetes (T2D) is a multifactorial disease that encompasses environmental risk factors and the contribution of multiple genomic variants. Studies on the genetic components of T2D revealed many T2D-associated ... -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Klionsky, Daniel; Abdel-Aziz, Amal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Alzaharna, Mazen; Aliwaini, Saeb (Informa UK Limited, 2021-01-02)In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and ... -
Hepcidin Status among Iron Deficient Anemic Pregnant Women in Gaza strip: A Case Control Study
Elnabaheen, Esraa; Alzaharna, Mazen; Zabout, Baker (Islamic University of Gaza, 2021-02)Background: Hepcidin, a peptide hormone composed of 25 amino acids. Hepcidin is synthesized mainly in the liver. Iron deficiency anemia (IDA) is common during pregnancy and is associated with higher maternal morbidity ... -
In vitro Anticancer Activity Effect of Extracellular Metabolites of Some Bacterial Species on HeLa Cell Line
Elmanama, Islam; Elmanama, Abderlraouf; AlZaharna, Mazen; Al Rifi, Mariam (IUGaza, 2020-01)Background: Cancer is still one of the most serious problems that affect human health. Despite the intense efforts to develop treatments, effective agents are still not available. In some cases, conventional therapy could ... -
In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine
Yang, Mei; AL Zaharna, Mazen Medhat; Chen, Yu-Shan; Li, LI; Cheung, Hon-Yeung (Royal Society of Chemistry, 2014)Abrus cantoniensis is a common and popular vegetative food consumed as beverage, soup and folk medicine in the tropical and subtropical areas of Asia. It has been claimed valuable for cleansing toxicants in the liver. ... -
Maternal Vitamin D Status in Gestational Diabetes Mellitus Women
Nassar, Zainedeen; Alzaharna, Mazen (Sciencedomain International, 2021-09-07)Aims: To assess vitamin D status among Gestational Diabetes Mellitus pregnant women in Gaza Strip. Study Design: Case control study. Place and Duration of Study: Samples were collected from pregnant women attending ... -
PROTEOMIC ANALYSIS OF GERMINATION-ASSOCIATED PROTEINS OF GEOBACILLUS STEAROTHERMOPHILUS
Wei, Dong; Qing, Shen; AL Zaharna, Mazen Medhat; Cheung, Hon-Yeung (2013)DONG, W, SHEN, Q, AL ZAHARNA, M & CHEUNG, HY 2013, 'PROTEOMIC ANALYSIS OF GERMINATION-ASSOCIATED PROTEINS OF GEOBACILLUS STEAROTHERMOPHILUS' Paper presented at International Symposium on Translating Omics Science to Clinical ... -
Relation of Iron Profile Parameters, Zinc and Magnesium with Febrile Seizures in Children from Gaza City
Shamallakh, Ohood; Shamallakh, Kholoud; Arafat, Heba; Alzaharna, Mazen (IOSR, 2021-04)Objective: To investigate the association between iron profile parameters, Zn, and Mg levels with febrile seizure (FS) among children in Gaza City. Materials and Methods: A case-control study, performed on 80 children ... -
Synergistic anticancer effect of combining metformin with olive (Olea europaea L.) leaf crude extract on the human breast cancer cell line MCF-7
Isleem, Rajy; Alzaharna, Mazen; Sharif, Fadel (AKINI PUBLISHERS, 2020-02)Breast cancer is one of the most prevalent cancers among women globally. Several in vitro studies have shown that Metformin and Olive (Olea europaea L.) Leaf extract have anticancer activity when applied separately. This ... -
Taxifolin enhances andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation
Zhang, Zhong Rong; AL Zaharna, Mazen Medhat; Wong, Matthew Man-Kin; Chiu, Sung-Kay; Cheung, Hon-Yeung (Public Library of Science, 2013)Andrographolide (Andro) suppresses proliferation and triggers apoptosis in many types of cancer cells. Taxifolin (Taxi) has been proposed to prevent cancer development similar to other dietary flavonoids. In the present ... -
Taxifolin synergizes Andrographolide-induced cell death by attenuation of autophagy and augmentation of caspase dependent and independent cell death in HeLa cells
AL Zaharna, Mazen Medhat; EL Qouqa, Iyad A; Cheung, Hon-Yeung (Public Library of Science (PLoS), 2017)Andrographolide (Andro) has emerged recently as a potential and effective anticancer agent with induction of apoptosis in some cancer cell lines while induction of G2/M arrest with weak apoptosis in others. Few studies ...