Now showing items 1-5 of 5

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      BIOACTIVE PROPERTIES OF IRON-CONTAINING CARBON

      Sawle, Philip; Hammad, Jehad; Fairlamb, Ian JS; Moulton, Benjamin; O'brien, Ciara T; Lynam, Jason M; Duhme-Klair, Anne K; Duhme-Klair, Anne-kathrin; Foresti, Roberta; Motterlini, Roberto (American Society for Pharmacology & Experimental Therapeutics (ASPET), 2006)
      Carbon monoxide-releasing molecules (CO-RMs) are compounds capable of delivering controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls (CORM-2 and CORM-3) and boronacorbonates (CORM-A1) have ...
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      Bioactive properties of iron-containing carbon monoxide-releasing molecules

      Sawle, Philip; Hammad, Jehad; Fairlamb, Ian JS; Moulton, Benjamin; O'brien, Ciara T; Lynam, Jason M; Duhme-Klair, Anne K; Foresti, Roberta; Motterlini, Roberto (American Society for Pharmacology and Experimental Therapeutics, 2006)
      Carbon monoxide-releasing molecules (CO-RMs) are compounds capable of delivering controlled amounts of CO within a cellular environment. Ruthenium-based carbonyls [tricarbonyldichloro ruthenium(II) dimer and tricarbonylc ...
    • CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule

      Motterlini, Roberto; Sawle, Philip; Hammad, Jehad; Bains, Sandip; Alberto, Roger; Foresti, Roberta; Green, Colin J (Federation of American Societies for Experimental Biology, 2005)
      SPECIFIC AIMS Carbon monoxide (CO) is emerging as an important and versatile mediator of physiological processes in that treatment of animals with exogenous CO gas has beneficial effects in a range of vascular and ...
    • Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule

      Foresti, Roberta; Hammad, Jehad; Clark, James E; Johnson, Tony R; Mann, Brian E; Friebe, Andreas; Green, Colin J; Motterlini, Roberto (Wiley/Blackwell (10.1111), 2004)
      Carbon monoxide (CO), one of the end products of heme catabolism by heme oxygenase, possesses antihypertensive and vasodilatory characteristics. We have recently discovered that certain transition metal carbonyls are capable ...
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      Vasorelaxing effects and inhibition of nitric oxide in macrophages by new iron-containing carbon monoxide-releasing molecules (CO-RMs)

      Motterlini, Roberto; Sawle, Philip; Hammad, Jehad; Mann, Brian E; Johnson, Tony R; Green, Colin J; Foresti, Roberta (Academic Press, 2013)
      Carbon monoxide-releasing molecules (CO-RMs) are a class of organometallo carbonyl complexes capable of delivering controlled quantities of CO gas to cells and tissues thus exerting a broad spectrum of pharmacological ...