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Please use this identifier to cite or link to this item:

http://hdl.handle.net/20.500.12358/24378
TitleAntihyperglycaemic effect of Saliva leriifolia Benth leaf and seed extract in mice.
Untitled
Abstract

The present study is aimed to assess the therapeutic potential of sulfonylurea drug glimepiride in comparison with Nerium oleander plant extract on insulin, glucose levels and some liver enzymes activities in streptozotocin-induced diabetic rats. Rats were rendered diabetic by intraperitoneal injection of a single dose of 50 mg kg-1 body weight streptozotocin. Rats with serum glucose levels >200 mg dL-1 were subdivided into three sub-groups: the first sub-group were remained without treatment and considered as diabetics. The second and third subgroups were orally administered 0.1 mg kg-1 body weight/day glimepiride and 250 mg kg-1 body weight/day Nerium oleander, respectively for 4 weeks. Streptozotocin-induced diabetic rats showed hypoinsulinemia and hyperglycemia compared to controls. Strong negative correlation (r = -0.8) was found between serum insulin and glucose levels in diabetic rats. This …

Authors
Mwafy, Saleh N
Yassin, Maged M.
Organization, World Health
George, M
Ayuso, E
Casellas, A
Costa, C
Devedjian, JC
Bosch, F
Setter, SM
Iltz, JL
Thams, J
Campbell, RK
Szkudelski, T
Ashour, Ara
Elyazji, Nehad R.
Krauss, H
Kozlik, J
Gryzymislawski, M
Sosnowski, P
Mikrut, K
Piatek, J
Paluszak, J
West, E
Simon, OR
Morrison, EY
Seifter, S
England, S
Baquer, NZ
El-Agouza, I
Rawy, A
Saad, A
Lashin, A
El-Sisi, S
Gawronska-Szklarz, B
Musial, DH
Pawlik, A
Paprota, B
Bando, K
Yamada, Y
Sato, J
Ohsawa, I
Oshida, Y
Sato, Y
Sakamoto, N
Ali, L
Azad-Khan, AK
Hassan, Z
Mosihuzzaman, M
Nahar, N
Grover, JK
Yadav, S
Vats, V
Haeba, MH
Mohamed, Abdurahman
Mehdi, AW
Nair, GA
Mythili, MD
Vyas, R
Akila, G
Gunasekaran, S
Nieszner, E
Posa, I
Kocsis, E
Pogatsa, G
Preda, I
Koltai, MZ
Adam, Sei
Al-Yahya, MA
Al-Farhan, AH
Travis, JC
Trinder, P
Thomas, L
Bessey, OA
Lowry, OH
Brock, MJ
Bogardus, C
Lillioja, S
Howard, V
Reaven, G
Mott, D
Hebden, RA
Gardiner, SM
Bennet, T
Macdonald, IA
Abu-Amra, E
Defranzo, RA
Simonson, DC
Cheta, DM
Lim, J
Chan, EK
Kunakorn, T
Charles, MA
Ashcroft, Sjh
Ashcroft, FM
Alberti, Kgmm
Zimmet, PZ
Defronzo, RA
Mondal, DK
Yousuf, BM
Banu, LA
Ferdousi, R
Shamim, KM
Yaniv, Z
Dafni, A
Friedman, J
Palevitch, D
Yanardag, R
Ozsoy-Sacan, O
Orak, H
Ozgey, Y
Tanaka, K
Ashour, Abd El Rahiem A.
Ashour, A
Ravi, K
Sivagnanam, K
Subramaniam, S
Hosseinzadeh, H
Khodaparast, Hmh
Shokohizadeh, H
TypeJournal Article
Date1999
Published inPakistan Journal of Biological Sciences
SeriesVolume: 14, Number: 21
Publisherorgz
Citation
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  • Staff Publications- Faculty of Medicine [149]
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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

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The institutional repository of the Islamic University of Gaza was established as part of the ROMOR project that has been co-funded with support from the European Commission under the ERASMUS + European programme. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein.

Contact Us | Send Feedback